Randomized control trial of intra-peritoneal instillation of bupivacaine versus placebo for post-operative analgesia after laparoscopic hysterectomy

Background: Laparoscopy is an established method to perform major surgeries, with many advantages over open surgeries. Hysterectomy a common procedure performed increased use of laparoscopy, having postoperative pain management issue. Effective promotes early ambulation, lowering the risk DVT and PE.Methods: The present study aimed assess effect bupivacaine intraperitoneally during laparoscopic hysterectomy reduce pain. 48 women undergoing under ASA I II general anesthesia were included, divided into 2 groups, group A receiving 0.25% intraperitoneally; B saline. blind observer observed both groups for 6 hours post-surgery or until VAS was 4, whichever came first, need rescue analgesia, side-effects, total dose analgesia required in 24 hours. Diclofenac sodium paracetamol used as groups.Results: There no significant difference reported demographic parameters between two groups. scores at 6, 12 after laparoscopy significantly lower than B. increase time 1st while amount low compared more number patients who needed opioids A.Conclusions: Peritoneal instillation found be useful saline (placebo), reduction analgesics period.